Conditional Random Fields (CRF) are frequently applied for labeling and segmenting sequence data. Morency et al. (2007) introduced hidden state variables in a labeled CRF structure in order to model the latent dynamics within class labels, thus improving the labeling performance. Such a model is known as Latent-Dynamic CRF (LDCRF). We present Factored LDCRF (FLDCRF), a structure that allows multiple latent dynamics of the class labels to interact with each other. Including such latent-dynamic interactions leads to improved labeling performance on single-label and multi-label sequence modeling tasks. We apply our FLDCRF models on two single-label (one nested cross-validation) and one multi-label sequence tagging (nested cross-validation) experiments across two different datasets - UCI gesture phase data and UCI opportunity data. FLDCRF outperforms all state-of-the-art sequence models, i.e., CRF, LDCRF, LSTM, LSTM-CRF, Factorial CRF, Coupled CRF and a multi-label LSTM model in all our experiments. In addition, LSTM based models display inconsistent performance across validation and test data, and pose diffculty to select models on validation data during our experiments. FLDCRF offers easier model selection, consistency across validation and test performance and lucid model intuition. FLDCRF is also much faster to train compared to LSTM, even without a GPU. FLDCRF outshines the best LSTM model by ~4% on a single-label task on UCI gesture phase data and outperforms LSTM performance by ~2% on average across nested cross-validation test sets on the multi-label sequence tagging experiment on UCI opportunity data. The idea of FLDCRF can be extended to joint (multi-agent interactions) and heterogeneous (discrete and continuous) state space models.

Convolution Neural Networks (CNN) have performed well in many applications such as object detection, pattern recognition, video surveillance and so on. CNN carryout feature extraction on labelled data to perform classification. Multi-label classification assigns more than one label to a particular data sample in a data set. In multi-label classification, properties of a data point that are considered to be mutually exclusive are classified. However, existing multi-label classification requires some form of data pre-processing that involves image training data cropping or image tiling. The computation and memory requirement of these multi-label CNN models makes their deployment on edge devices challenging. In this paper, we propose a methodology that solves this problem by extending the capability of existing multi-label classification and provide models with lower latency that requires smaller memory size when deployed on edge devices. We make use of a single CNN model designed with multiple loss layers and multiple accuracy layers. This methodology is tested on state-of-the-art deep learning algorithms such as AlexNet, GoogleNet and SqueezeNet using the Stanford Cars Dataset and deployed on Raspberry Pi3. From the results the proposed methodology achieves comparable accuracy with 1.8x less MACC operation, 0.97x reduction in latency and 0.5x, 0.84x and 0.97x reduction in size for the generated AlexNet, GoogleNet and SqueezeNet CNN models respectively when compared to conventional ways of achieving multi-label classification like hard-coding multi-label instances into single labels. The methodology also yields CNN models that achieve 50\% less MACC operations, 50% reduction in latency and size of generated versions of AlexNet, GoogleNet and SqueezeNet respectively when compared to conventional ways using 2 different single-labelled models to achieve multi-label classification.

Development of interpretable machine learning models for clinical healthcare applications has the potential of changing the way we understand, treat, and ultimately cure, diseases and disorders in many areas of medicine. Interpretable ML models for clinical healthcare can serve not only as sources of predictions and estimates, but also as discovery tools for clinicians and researchers to reveal new knowledge from the data. High dimensionality of patient information (e.g., phenotype, genotype, and medical history), lack of objective measurements, and the heterogeneity in patient populations often create significant challenges in developing interpretable machine learning models for clinical psychiatry in practice. In this paper we take a step towards the development of such interpretable models. First, by developing a novel categorical rule mining method based on Multivariate Correspondence Analysis (MCA) capable of handling datasets with large numbers of feature categories, and second, by applying this method to build a transdiagnostic Bayesian Rule List model to screen for neuropsychiatric disorders using Consortium for Neuropsychiatric Phenomics dataset. We show that our method is not only at least 100 times faster than state-of-the-art rule mining techniques for datasets with 50 features, but also provides interpretability and comparable prediction accuracy across several benchmark datasets.